While there are many different kinds of antidepressants, they are all toxic to your dog if enough is ingested. Tricyclic antidepressants are the most dangerous because they can affect the heart and central nervous system within minutes, and be fatal if not treated right away, depending on the amount ingested and size of the dog. Cardiac arrhythmia, tachycardia, and bradycardia are common and have to be addressed as soon as possible after ingestion or it can be fatal. It is true that veterinarians sometimes prescribe antidepressants to dogs for certain conditions, but even with small doses, side effects can always occur. One of the top 10 poisonings in dogs is caused by antidepressant medicines, such as selective serotonin reuptake inhibitors (SSRIs), tricyclics (TCAs), monoamine oxidase inhibitors (MAOIs), and Novel antidepressants. Although antidepressant poisonings share many symptoms, they each have some unique symptoms that should be noted. 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Because he has ingested 3 times this amount, we could see some profound lethargy and sedation with this dose potentially and to be on the safe side, you should try to get your boy to bring this back up. There are several ways to induce vomiting in dogs and if you wanted to try from home you can do so with a little hydrogen peroxide. You can find all the info you need on how to do this here: he has ingested this tablet in the last hour or two, you should notice it come up in the vomitus. Best of luck with your boy and let me know how you get on. Don't forget to click an excited face :-D if this has been helpful. Zoloft dogs Antidepressants Poisoning in Dogs - Symptoms,, My dog ate my 100 mg Zoloft pill. 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