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    PAGE 4 PAGE 2 Version No.: Product Name: LF-102166-01 Revision No.: Revision Date: Revised by: CRF: Prednisolone 5mg Suppositories 10 Suppositories Leaflet 103482 UK Haupt Pharma Livron Sas 2 04/04/2017 ADD PR 9396 Dimension: Commodity No.: Pharma Code: Core Spec Ref: DCMF: Print Colours: 210 x 157 mm 54000030 N/A N/A N/A 302 C Pack Size: Component: SKU: Market: Production Site: Non-Print Colours: Cutter Tech App. Font Size: 13/02/2017 9 pt LF-102166-01 Additional care should be taken if this • Higher blood pressure • Increased pressure in the eye (glaucoma) • Cataracts • Worsening of viral or fungal eye diseases • Thinning of the cornea or sclera (the outer wall of the eye) • Detachment of the retina • Headaches or blurred vision • Wasting of muscles • Breaking of tendons. Symptoms can include hearing or feeling a pop or a snap, severe pain, immediate bruising and an inability to put weight on or use the affected area • If you have recently had a heart attack, prednisolone can cause the tissues of the heart to tear • Severe stomach pain • Stomach ulcers which may bleed • Irregular menstrual periods • Acne or extra hair growth • Weight gain or increased appetite • Increased risk of infection • Water retention • Low levels of potassium in your blood • Bruising or poor wound healing • Inflammation of the skin, abscesses or changes in skin colour • Separation of the top layer of the skin from the lower skin layers • Blood clots • Changes in blood test results for lipids (e.g. cholesterol) • Thrush in the mouth or throat • Feeling sick, hiccups, heartburn or indigestion • Fungal infection (candidiasis) • Loss of blood to your bones (avascular osteonecrosis) • Bone fractures. Keep this medicine out of the sight and reach of children. Do not use this medicine after the expiry date which is stated on the label. The expiry date refers to the last day of that month. Store below 25ºC and keep the suppositories in the outer carton to protect from light. Do not throw away any medicines via wastewater or household waste. How to store Prednisolone 5mg Suppositories Reporting of side effects If you get any side effects, talk to your doctor, pharmacist or nurse. Prednisolone is a glucocorticosteroid which is about four times as potent as hydrocortisone on a weight for weight basis. Prednisolone 5mg Suppositories are indicated for the treatment of haemorrhagic and granular proctitis and the anal complications of Crohn's disease. Adults and paediatric population: One suppository inserted at night and one in the morning after defaecation. When the response is good, treatment is usually continued for some months. If symptoms recur later, treatment should be resumed. Although Prednisolone 5mg Suppositories are applied locally, it should be borne in mind that there is likely to be substantial systemic absorption, especially when the bowel is inflamed. Undesirable effects may be minimised by using for a minimum period.

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