It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. How long for chloroquine to work Revised recommendations on screening for chloroquine and hydroxychloroquine Mar 08, 2017 Many patients treated with hydroxychloroquine receive a dosage that exceeds the recommended maximum, boosting the retinal damage risk. Adults 800 mg 620 mg base followed by 400 mg 310 mg base at 6 hours, 24 hours and 48 hours after the initial dose total 2000 mg hydroxychloroquine sulfate or 1550 mg base. Oct 29, 2018 In 2016, a revised version of the guidelines recommended a maximum dose of 5 mg/kg based on actual weight, with an examination at baseline and repeat screening — via optical coherence tomography. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis (or juvenile idiopathic arthritis) and other autoimmune diseases. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Aximum dose of plaquenil Plaquenil Dosage Guide -, Plaquenil - FDA prescribing information, side effects and uses Is plaquenil still availablePlaquenil toxicity visual fieldAralens.irGeneric drug for plaquenilHydroxychloroquine uses Background/Purpose Hydroxychloroquine HCQ is a widely-used medication in many rheumatologic conditions. The most worrisome toxicity is irreversible damage to retinal pigment epithelium which can lead to blindness. The most recent 2016 guidelines from the American Academy of Ophthalmology AAO recommend the dose of HCQ ≤5 mg/kg real body weight to minimize toxicity1. According to these New Guidelines on Hydroxychloroquine Dosage - Where Are We.. Experts debate hydroxychloroquine dosing guidelines in lupus. Protecting your eyesight when taking Plaquenil Lupus.. How to use Plaquenil. Hydroxychloroquine is usually taken with food or milk to prevent stomach upset. The dosage and length of treatment are based on your medical condition and response to therapy. In children, dosage is also based on weight. The usual dosage works for most people who take Plaquenil, but it is possible to increase or decrease the dose based on individual needs. It's important to watch for possible side effects and toxicity. For people who weigh less than 80 kg, a lower daily dose is prescribed, up to a maximum of 5 mg/kg of body weight. Feb 19, 2020 To treat malaria Hydroxychloroquine is usually given for 3 days, starting with one high dose followed by a smaller dose during the next 2 days in a row. Take this medicine for the full prescribed length of time for malaria.