It is used to prevent and treat acute attacks of malaria. It is also used to treat discoid or systemic lupus erythematosus and rheumatoid arthritis in patients whose symptoms have not improved with other treatments. Intermittent preventive therapy chloroquine Chloroquine generic Chloroquine protein synthesis Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. PLAQUENIL prescription and dosage sizes information for physicians and healthcare professionals. Pharmacology, adverse reactions, warnings and side effects. The two types of antimalarials most often prescribed today for lupus are hydroxychloroquine Plaquenil® and chloroquine Aralen®. Unlike the rapid response seen with steroids, it may take months before antimalarial drugs improve your lupus symptoms. Side effects from antimalarials are rare and usually mild. Hydroxychloroquine comes as a tablet to take by mouth. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information. Plaquenil drug class Plaquenil hydroxychloroquine sulfate dosing, indications., PLAQUENIL Dosage & Rx Info Uses, Side Effects Does hydroxychloroquine cause fatigueMefloquine or plaquenil Plaquenil hydroxychloroquine belongs to a group of medicines called quinolines. Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Plaquenil Uses, Dosage & Side Effects -. Medications used to treat lupus Lupus Foundation of America. Plaquenil Dosage Guide -. Adults. 200 mg 155 mg base to 400 mg 310 mg base PO per day, administered as a single dose or in 2 divided doses. Antimalarials and/or glucocorticoids are of benefit and may be used for the treatment of SLE without major organ manifestations; however, judicious use of hydroxychloroquine is recommended. Hydroxychloroquine is in a class of drugs called antimalarials. It is used to prevent and treat acute attacks of malaria. It is also used to treat discoid or systemic lupus erythematosus and rheumatoid arthritis in patients whose symptoms have not improved with other treatments. Plaquenil and Azulfidine belong to different drug classes. Plaquenil is an antimalarial medication and Azulfidine EN-tabs is an anti- inflammatory agent and immunomodulatory agent. Side effects of Plaquenil and Azulfidine that are similar include nausea, vomiting, loss of appetite, diarrhea, dizziness, spinning sensation, headache, ringing.