Hydroxychloroquine induced rash

Discussion in 'International Pharmacy' started by YashkaDurashka, 09-Mar-2020.

  1. armnet New Member

    Hydroxychloroquine induced rash


    B, Brown pigmentation on the legs in another patient who had systemic lupus erythematosus associated with diffuse discoid lupus. The skin biopsy was performed on the brown area distant from discoid lesions.

    98 hydroxychloroquine Hydroxychloroquine toxicity

    Cutaneous adverse reactions to hydroxychloroquine have been described, including acute generalized exanthematous pustulosis 11, 12, Stevens-Johnson syndrome 13, and toxic epidermal necrolysis 14–16. Here we report a case of hydroxychloroquine-induced erythema multiforme after 12 days of exposure in a 25 year old woman with lupus. Hydroxychloroquine is an antimalarial drug that is also used in the treatment of various rheumatic diseases including systemic lupus erythematous SLE. Various adverse reactions include skin rash, diarrhea, nausea and retinopathy were reported 1. Hydroxychloroquine induced myopathy is a rare side effect and reported prevalence is up to 6.7% 2. Very rare presentation of hydroxychloroquine toxicity. CASE PRESENTATION 36 year old female presented with fever, malaise, chills and a lip rash for 3 days past history included eosinophilic fasciitis being treated with methotrexate for 2 years which was stopped due to intolerence 3 weeks ago and she was started on hydroxychloroquine 300mg daily. Investigation revealed WBC 300.

    B, Presence of iron in the same areas of the dermis (Perls staining, original magnification ×100). Pub Med Google Scholar Crossref Morrison LK, Nordlund JJ, Heffernan MP. Pub Med Google Scholar Costedoat-Chalumeau N, Galicier L, Aumaître O, et al; Group PLUS. Google Scholar Costedoat-Chalumeau N, Amoura Z, Hulot JS, et al. Pub Med Google Scholar Crossref Costedoat-Chalumeau N, Leroux G, Piette J-C, Amoura Z. A, Interstitial and perivascular brown pigmented granules in the dermis (hematoxylin-eosin-safran staining, original magnification ×100).

    Hydroxychloroquine induced rash

    Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria, A Rare but Reversible Cause of Myopathy.

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  6. Feb 19, 2020 SIDE EFFECTS. The following adverse reactions have been identified during post-approval use of PLAQUENIL or other 4-aminoqunoline compounds. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.

    • Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses.
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    • Side Effects of Plaquenil Hydroxychloroquine,.

    Background Hydroxychloroquine sulfate and other antimalarial drugs have been used successfully as adjunctive therapy for patients with cutaneous lesions of dermatomyositis over the past 20 years. An increased incidence of cutaneous reactions to hydroxychloroquine has been postulated to occur in patients with dermatomyositis. This article is from June 2011 and may contain outdated material. Download PDF. Many systemic medications may cause retinal toxicity. One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine Plaquenil, a chloroquine derivative. Hydroxychloroquine typically is very well tolerated. Serious side effects are rare. The most common side effects are nausea and diarrhea, which often improve with time. Less common side effects include rash, changes in skin pigment such as darkening or dark spots, hair changes, and muscle weakness.

     
  7. Ladimir User

    This is not a list of all drugs or health problems that interact with chloroquine. Chloroquine - Drugs and Lactation Database LactMed - NCBI. Malaria prophylaxis – what can be given to breastfeeding. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses
     
  8. fomd Moderator

    Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus Plaquenil hydroxychloroquine is a medication most known for its original purpose of treating or preventing malaria, a disease caused by parasites that enter the body through the bite of a mosquito.

    Medicines for the Prevention of Malaria While Traveling.
     
  9. Silus XenForo Moderator

    Mechanism of action of hydroxychloroquine as an. Mechanism of action of hydroxychloroquine as an antirheumatic drug. Fox RI1. Author information 1Department of Rheumatology, Scripps Clinic and Research Foundation, La Jolla, CA 92037. The antimalarial agents chloroquine and hydroxychloroquine have been used widely for the treatment of rheumatoid arthritis and systemic lupus erythematosus.

    Hydroxychloroquine Plaquenil Side Effects & Dosage for.