In many cases, once the offending drug has been stopped, fading of the lesions occurs. However, the pigmentation may last a long time or become permanent. Can i take metformin and plaquenil together Hydroxychloroquine schnitzler syndrome urticaria Lariago chloroquine phosphate 250 mg Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis, prevent joint damage and reduce the risk of long- term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Skin rashes and pigment change. Atabrine, specifically, can cause yellow pigmentation of skin. Sometimes Plaquenil can also deposit in the tissues of the body and cause the skin to take on a greenish tone. Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. Applies to hydroxychloroquine: oral tablet Along with its needed effects, hydroxychloroquine (the active ingredient contained in Plaquenil) may cause some unwanted effects. Because many drugs that induce skin pigmentation also cause photosensitivity reactions, sun protection is usually recommended. Plaquenil skin pigment Pigmentation and Plaquenil Hi, its been 1.6 yrs., Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus. Plaquenil and tinnitusChloroquine lysosome inhibitor mechanismPlaquenil and liver toxicityStopping and starting plaquenil Skin hyperpigmentation is found among people who take Plaquenil, especially for people who are female, 50-59 old, have been taking the drug for 5 - 10 years, also take medication Omniscan, and have Arteriogram. Will you have Skin hyperpigmentation with Plaquenil.. Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria. Skin Discoloration and Plaquenil - Arthritis Information. Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as. The skin lesions were macular or patchy, some well and others poorly demarcated, with a hyperpigmentation of gray to black discoloration, generally annular, but some with irregular morphology. They were flat without induration or scaling Figure 1. A known side effect of using antimalarials long term is dark patches on the skin. The Lupus Encyclopedia Thomas Jr. 2014 says this 'One of the potential long-term side-effects of using anti-malarial medications such as hydroxychloroquine Plaquenil, chloroquine, and quinacrine is the development of dark-colored patches on the skin.