Hydroxychloroquine is available as the brand-name drug Plaquenil. Generic drugs usually cost less than the brand-name version. Hydroxychloroquine may be used as part of a combination therapy. What will happen if i don't take plaquenil Hydroxychloroquine ok to stop Taking methotrexate with hydroxychloroquine has not been studied. It may increase your risk of side effects. Taking cyclosporine with hydroxychloroquine can increase the amount of cyclosporine in. Methotrexate–hydroxychloroquine combination therapy may cause lower disease activity in early RA than methotrexate monotherapy. Methotrexate monotherapy as first early RA treatment seems to lead to more treatment intensification. I haven't had any issues with Plaquenil, and I've been on it for 13 years. Be sure you get your eyes checked regularly for Plaquenil toxicity, a very rare side effect that can affect your vision, but is usually reversible if caught early. I know Plaquenil has helped me a ton, because I tried going off of it once to see if I really needed it. Hydroxychloroquine is used to treat lupus erythematosus and rheumatoid arthritis. It isn’t fully understood how this drug works to treat lupus erythematosus or rheumatoid arthritis. That means you may need to take it with other drugs. It treats malaria by killing the parasites that cause the disease. Methotrexate trexall and hydroxychloroquine plaquenil Methotrexate vs Plaquenil? -, Effects of methotrexate and hydroxychloroquine combination. Plaquenil oct image Methotrexate may be considered for the treatment of psoriasis or rheumatoid arthritis if other treatments have failed. It may also be used in certain cancers. Side effects can be severe and. Methotrexate vs Plaquenil Comparison -. Methotrexate vs. Plaquenil - Autoimmune diseases - Inspire. Combination therapy with methotrexate and.. I was diagnosed with RA in march and have been on increasing dose of methotrexate. Yesterday my rheumatologist started me on hydroxychloroquine as well. Is anyone else on this combination and have you had any problems with it as I know hydroxychloroquine can cause eye sight problems. Thanks Methotrexate Rheumatrex®, Trexall® Hydroxychloroquine Plaquenil ® Sulfasalazine Azulfidine® Leflunomide Arava® Tumor Necrosis Factor Inhibitors— etanercept Enbrel®, adalimumab Humira ®, and infliximab Remicade® T-cell Costimulatory Blocking Agents—abatacept Orencia® B cell Depleting Agents—rituximab Rituxan® Trexall methotrexate, Barr Laboratories was first developed as a form of chemotherapy and continues to be used as such; however, this drug has gained popularity as an effective DMARD agent. 23 It has been shown to cause certain ocular side effects even at low doses a typical dose may be 2.5mg orally two to three times per week, the most.