Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Plaquenil side effects dry mouth Plaquenil for hives Yes, plaquenil can cause low blood sugars. Eat frequent meals with carbs and protein but good carbs with fiber like oatmeal or whole wheat toast with peanut butter. I like the lowered blood sugar effect b/c I have type 2 diabetes but before I got type 2, I had some low sugars with plaquenil for sure. Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. I was just about to write a post on about this then i saw this post, iv been on plaquenil for about 4 years and looking back about 2 years r more my moods have been all over the place one day im fine and happy next day like today all i want to do in hide in my bed and cry, is this a lupus thing r am i depressed? / Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil cause dizziness after 2 years Common and Rare Side Effects for Plaquenil Oral, Plaquenil Oral Uses, Side Effects, Interactions, Pictures. Plaquenil insomnia First, my mother and sister took plaquenil for lupus with good effect, so I am not just disliking it for no good reason. I also suffer from disabling bipolar disorder. For 25 years, I have gotten hypomanic during spring. Very happy, never depressed. When I started taking Plaquenil, I got a bit depressed but that's not a big deal. PLAQUENIL Side Effects, Reviews by Patients -. Anxiety and Plaquenil Has anyone experienced mood. - LUPUS UK. Plaquenil Withdrawal – Life As An Anomaly. Fever that happens while in or after coming back from the malaria area. What are some other side effects of Plaquenil? All drugs may cause side effects. However, many people have no side effects or only have minor side effects. According to Drugs.com, Plaquenil given for a long term can cause retinal disorders after a few months or years of daily use--especially if the dose exceeds 400mg per day. The risk of retinal damage increases at doses of 600mg to 700mg. Malaria The recommended preventative adult dose is 400 mg on exactly the same day of each week, beginning 2 weeks before exposure and continued for 8 weeks after leaving the high-risk area. Children's doses are based on body weight and are calculated as 5 mg of hydroxychloroquine base per kilogram of body weight to a maximum dose of 400 mg.