Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Plaquenil sore mouth Long term effects of plaquenil Whichhis worse plaquenil or methotrexate The active ingredient in hydroxychloroquine is hydroxychloroquine sulfate. 4. How does hydroxychloroquine work? Hydroxychloroquine is an antimalarial drug. It is derived from quinine and cinchonine, which were originally taken from the bark of the cinchona tree found in Peru. Antimalarials modulate or change the way the immune system works. Antimalarials are used extensively in both RA and SLE. The major side effect is retinal toxicity, which requires ophthalmologic monitoring every 6–12 months. The favored antimalarial is hydroxychloroquine FDA Category C, which appears to have a lower incidence of retinal toxicity. There is no vaccine or antiviral treatment for human coronavirus, so this study aims to evaluate the efficacy and safety of hydroxychloroquine in the treatment of pneumonia caused by the 2019 novel coronavirus. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Antimalarials hydroxychloroquine Hydroxychloroquine and Antimalarials The Journal of., Antimalarial Agent - an overview ScienceDirect Topics Hydroxychloroquine mechanismPlaquenil and visual field testingVd chloroquineChloroquine and immune complement activationPlaquenil and b12 Hydroxychloroquine belongs to a group of medicines known as antimalarials. It works by preventing or treating malaria, a red blood cell infection transmitted by the bite of a mosquito. However, this medicine is not used to treat severe or complicated malaria. Hydroxychloroquine Oral Route Description and Brand Names.. Efficacy and Safety of Hydroxychloroquine for Treatment of.. Hydroxychloroquine - Wikipedia. Chloroquine and hydroxychloroquine have not been given a formal green light in the US to fight the pandemic, but the Food and Drug Administration FDA said it would work with domestic makers to. Hydroxychloroquine Plaquenil™ What is hydroxychloroquine? Hydroxychloroquine also known as hydroxychloroquine sulfate is an arthritis medicine. that also can be used to prevent malaria. It is available in the United States by prescription only. It is sold under the brand name Plaquenil and it is also sold as a generic medicine. It is. The antimalarials most often prescribed to people with lupus are Hydroxychloroquine Plaquenil® Chloroquine Aralen® Quinacrine Atabrine® 2-3; Hydroxychloroquine is prescribed the most often because it is thought to have the fewest side effects. Chloroquine and quinacrine are prescribed when hydroxychloroquine cannot be used.