Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Chloroquine primaquine combination How good is plaquenil for diabetes Besides its glucose-lowering effect in patients with diabetes, lower fasting blood sugar levels Penn et al. 2010, as well as hypoglycemia have also been reported with CQ and HCQ in subjects without diabetes Abu-Shakra and Lee, 1994; Cansu and Korkmaz, 2008; Winter et al. 2011. Interestingly, HCQ lowers the incidence of developing diabetes mellitus. I found some literature that says that plaquenil can lower your blood sugar, but the stuff I found only mentioned reductions of about 5 mg/dl. Has anyone here had problems with blood sugar that was. This medication may rarely cause low blood sugar hypoglycemia. Tell your doctor right away if you develop symptoms of low blood sugar, such as sudden sweating, shaking, fast heartbeat, hunger. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria. Can plaquenil cause low blood sugar Hypoglycaemia and hydroxychloroquine This might seem., Plaquenil/hydroxychloroquine and hypoglycemia" Lupus Community. Plaquenil poisoningPlaquenil red spotsCan i take mucinex d with plaquenil Taking hydroxychloroquine with these drugs could cause hypoglycemia low blood sugar. Your doctor may need to reduce your dosage of insulin or the other diabetes drugs. Examples of other diabetes. Hydroxychloroquine Side Effects, Dosage, Uses, and More. Plaquenil Oral Uses, Side Effects, Interactions.. Does Lupus cause low.low blood sugar? Lupus.. Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Also if your doing more exercise, it will also bring down your sugar much quicker. After exercising have some Orange juice, and a Carb. My sugar has lately been swinging both ways very quickly. Very high, and then after exercise to very low. Not able to control mine by diet, any more. Gastro doctor wants me on insulin. Hugs Blood sugar levels Hydroxychloroquine may cause hypoglycemia low blood sugar levels. People with diabetes may find it necessary to monitor their blood sugar more frequently while using this medication. People without diabetes have also been known to experience low blood sugars while taking hydroxychloroquine.