But Chloroquine has significantly higher rate of retinal toxicity, so it isn't used much anymore. Also, Plaquenil appears to effectively reduce flares in patients with lupus not necessarily by suppressing immunity. Read more Anxiety over potential eye problems with Hydroxychloroquine is completely unwarranted if the dose is kept below 6mg/kg (2.2lbs) of body weight. Read more See 1 more doctor answer It can cause eye problems so you need to see an ophthalmologist and peridoic screenings. Read more Results are very good, particulary when used alone and better with methotrexate. Hydroxychloroquine lupus dosage Plaquenil guidelines aao 2016 I just wanted to let you know that I am highly allergic to sulfa drugs and have been on plaquenil for almost 8 years with no problems at all. I did accidentally take a sulfa drug about 5 years ago and still had the horrible reaction so know I'm still allergic even while being on plaquenil. I was dx in August with Lupus and my Rheumy said she was afraid to start me on Plaquenil since I had a bad reaction to a Sulfa antibiotic I took and the same reaction when a Dr gave me Lasix. I read that the sulfa in Plaquenil is different from those in antibiotics and most people with Lupus have an allergy to Sulfa but can take Plaquenil without any problems. Submitted 2 years ago * by vadegarys. So after three weeks of taking Plaquenil hydroxychloroquine I developed a rash and had to stop. Now I'm really worried since Plaquenil is supposed to be the 'life insurance' drug of lupus, people have less flares on it, live longer, etc. Chloroquine can be substituted for Plaquenil but only in limited circumstances. Please provide more detailed information if you want a more specific answer. Read more See 1 more doctor answer Depends on what you are being treated for.... Read more While plaquenyl is a slow acting but effective drug, Prednisone is used in much higher doses in active sle. Arthritis (non-deforming) or arthralgias associated with the disease will have substantial pain relief with a dose this low. It's infusion intervals are longer, because the turnover of recptors is slower than the production of tnf-a itself. So other meds like Imuran and Cell Cept (mycophenolate mofetil) also reduce flares, but also increases infection. Read more It depends why you are taking Plaquenil in the first place. Apart from some stomach quiziies, I have never stopped this drug, as long as it demonstrated it is working. Other than that we see a few people who have increased skin pigmentation called "plaquenil ochronosis". The dirrence with Remicade (infliximab) is that it blocks the tnf-a receptor, rather than binding tnf-a itself, but it accomplishes the same thing. I have lupus am allergic to plaquenil substitute Plaquenil when allergic to sulfa? Lupus Forums at The Lupus Site, Plaquenil and Sulfa Allergies" Lupus Community - Support Group Plaquenil price in u.s.a Alternatives to Methotrexate self.lupus submitted 4 hours ago by auscientist. I have a long list of medication that I am allergic to including NSAIDs and plaquenil. A few years ago at the time she finally had enough evidence to call lupus not zero-negative RA we tried methotrexate. Alternatives to Methotrexate lupus. Allergic to Plaquenil. What now? lupus - reddit. Plaquenil allergy - Lupus - MedHelp. C-Quinicrin is an alternative to Plaquenil that worked REALLY well for me. The last I heard it was no longer in the US, so I have been been without it and feel miserable. Has anyone found a way to buy it in Canada or elsewhere. I am hurting here in California. I cannot take Plaquenil. To treat lupus erythematosus, the average adult dose is 400 mg once or twice daily. Plaquenil may interact with acetaminophen, cancer medications, tuberculosis medications, birth control pills or hormone replacement therapy, arthritis medications, ACE inhibitors, antibiotics, antifungals, cholesterol medications. Before using Plaquenil, tell your doctor if you are allergic to any drugs, or if you have psoriasis, porphyria, liver disease, alcoholism, or glucose-6-phosphate dehydrogenase G-6-PD deficiency. Take Plaquenil for the full prescribed length of time for malaria. Your symptoms may improve before the infection is completely cleared.