Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Normal dosage of plaquenil for lupus Taking plaquenil without food In 2014, its efficacy to treat Sjögren syndrome was questioned in a double-blind study involving 120 patients over a 48-week period. Hydroxychloroquine is widely used in the treatment of post-Lyme arthritis. It may have both an anti-spirochaete activity and an anti-inflammatory activity, similar to the treatment of rheumatoid arthritis. Brian M. Wolpin, MD, MPH - Medical Oncology. Dr. Wolpin received his medical degree from Harvard Medical School in 2001. He subsequently completed his residency in Internal Medicine at Brigham and Women's Hospital, and his fellowship in Medical Oncology at the Dana-Farber Cancer Institute. Wolpin BM, Rubinson DA, Wang X, Chan JA, Cleary JM, Enzinger PC, Fuchs CS, McCleary NJ, Meyerhardt JA, Ng K, Schrag D, Sikora AL, Spicer BA, Killion L, Mamon H, Kimmelman AC. Phase II and pharmacodynamic study of autophagy inhibition using hydroxychloroquine in patients with metastatic pancreatic adenocarcinoma. Oncologist. 2014 Jun; 196637-8. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Wolpin oncologist 2014 hydroxychloroquine Oncotarget Hydroxychloroquine and risk of cancer in., Brian M. Wolpin, MD, MPH - Dana-Farber Cancer Institute. Hydroxychloroquine visual field testNursing responsibility of chloroquinePricing on plaquenil at sam'sMalaria hydroxychloroquine resistanceWhy does plaquenil make my stomach bleed Mar 17, 2019 Hydroxychloroquine is a quinoline medicine used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Hydroxychloroquine Uses, Dosage & Side Effects -. Find a Doctor - Kimmie Ng, MD, MPH - Dana-Farber Cancer Institute. Phase II and Pharmacodynamic Study of. - PubMed Central PMC. Jun 09, 2017 Wolpin BM, Rubinson DA, Wang X, et al. Phase II and pharmacodynamic study of autophagy inhibition using hydroxychloroquine in patients with metastatic pancreatic adenocarcinoma. Oncologist. 2014;7–638. Phase II and Pharmacodynamic Study of Autophagy Inhibition Using Hydroxychloroquine in Patients With Metastatic Pancreatic Adenocarcinoma Article PDF Available in The Oncologist 196 May. Thirteen were treated in cohorts of three patients each with escalating hydroxychloroquine doses 200 and 400 mg and an extension phase at the 400-mg dose. The most common adverse events were mucositis, headache, and diarrhea. No drug-related serious adverse events were reported.