This medicine is also sometimes given off-label to help the following conditions: Also, let your doctor know if you drink large amounts of alcohol before starting on this medicine. Your doctor will probably want to order frequent tests to check your body's response to chloroquine. Plaquenil taper Plaquenil for thromboembolism Chloroquine cancer therapy Dec 04, 2014 The AAO guidelines defined high-risk patients by any one of the following criteria HCQ treatment 5 years in duration, HCQ dose 6.5 mg/kg/day, significant renal or hepatic disease, preexisting maculopathy due to other etiology, age 60 years, obesity, or cumulative HCQ consumption of 1000 g. For individuals with significant risk factors daily dose of chloroquine phosphate greater than 2.3 mg/kg of actual body weight, subnormal glomerular filtration, use of tamoxifen citrate or concurrent macular disease monitoring should include annual examinations which include BCVA, VF and SD-OCT. Etiology and Pathogenesis Choroquine retinopathy is caused by the ingestion of chloroquine or its related sulfates and disulphates of over 250 mg per day to a total exceeding 500 mg. Epidemiology Let your healthcare provider know if your symptoms either don't improve or worsen while taking this medicine. Keep all appointments with your doctor and laboratory. Chloroquine retinopathy dose Chloroquine - FDA prescribing information, side effects., CHLOROQUINE PHOSPHATE, USP Chloroquine diphosphate lysosome Depending on the specific disease, patients may be treated with either a chronic maintenance or acute high-level dose of chloroquine. A daily dose of chloroquine 3 mg/kg and a treatment duration of 5 years are considered important risk factors for the development of retinopathy Post-exposure Chloroquine Prophylaxis COVID19. Chloroquine Retinopathy Symptoms, Diagnosis and Treatment.. Recommendations on Screening for Chloroquine and.. The dose of chloroquine is often expressed or calculated as the base each 500 mg tablet of chloroquine phosphate is equivalent to 300 mg chloroquine base. -The pediatric dose should never exceed the adult dose. Dose equivalence and conversion. Doses expressed as chloroquine base. Each tablet contains 155 mg of chloroquine base equivalent to 250 mg of chloroquine phosphate. Syrup contains 50 mg/5 mL of chloroquine base equivalent to 80 mg/5 mL of chloroquine phosphate. Both adults and children should take one dose of chloroquine per week starting at least 1 week before. traveling to the area where malaria transmission occurs. They should take one dose per week while there, and for 4 consecutive weeks after leaving. The weekly dosage for adults is 300mg base 500mg salt.