Additionally, another exception occurred while executing the custom error page for the first exception. Ototoxicity is, quite simply, ear poisoning (oto = ear, toxicity = poisoning), which results from exposure to drugs or chemicals that damage the inner ear or the vestibulo-cochlear nerve (the nerve sending balance and hearing information from the inner ear to the brain). Lariago chloroquine phosphate 250 mg Hydroxychloroquine dose adjustment Hydroxychloroquine gingival hyperplasia Chloroquine is sometimes tolerated by patients who do not tolerate hydroxychloroquine. Ophthalmologic retinal and visual field testing should be performed at baseline or soon after drug initiation and then at 6 -12 month intervals. Ototoxicity have been found when these medications are taken orally in high doses by people with chronic kidney disease. Quinine • chloroquine phosphate Aralen •quinacrine hydrochloride Atabrine •quinine sulfate Quinam The ototoxic effects are very similar to those of aspirin. Mucosal Protectant • misoprostol Cytotec Narcotic. Ototoxicity can affect anyone receiving treatment from the medications listed above. However, the likelihood of developing ototoxicity is highly dependant on which drug is being administered, duration of use, and several other underlying factors, such as kidney function and the use of other ototoxic drugs at the same time. The parts of the brain that receive hearing and balance information from the inner ear can also be affected by poison, but this is not technically considered ototoxicity and won’t be covered in this information sheet. Because the inner ear is involved in both hearing and balance, ototoxicity can result in disturbances of either or both of these senses. Chloroquine ototoxicity Chloroquine ototoxicity Request PDF - ResearchGate, Ototoxic Medications - Northern Virginia Resource Center 25 μm chloroquine diphosphateWhere to order plaquenilLong term plaquenil use and electrolyte imbalanceChloroquine pretreatment degradation toxicity Ototoxicity at therapeutic doses is limited Aminoglycosidic antibiotics e.g. streptomycin, gentamycin and some other antibiotics e.g. tetracyclines, Loop diuretics* e.g. furosemide, ethacrynic acid Certain analgesics* and antipyretics* salicylates, quinine, chloroquine Preventing Hearing Loss Caused by Chemical Ototoxicity and Noise Exposure. Ototoxicity HealthEngine Blog. American Ear Hearing and Audiology LLC - Ototoxic Medications List. Chloroquine is related chemically to quinine and, because of this similarity, has been suspected of being an ototoxic drug. 1 It is currently being used for the treatment of malaria, amebiasis, rheumatoid Ototoxic Drugs The following list contains drugs that can have a temporary or permanent effect on hearing such as hearing loss or tinnitus. They were identified through the reading of Dr. Susan Kunkel from the Poison Center at the University of New Mexico College of Pharmacy where she is a Toxicology Fellow. This article is from June 2011 and may contain outdated material. Download PDF. Many systemic medications may cause retinal toxicity. One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine Plaquenil, a chloroquine derivative.