My skin turns red, and it feels like something is biting me. It's bad around my ankles and the tops of my feet, my arms, and I get red blotches and spots on my chest. Plaquenil and acetaminophen Hydroxychloroquine for ankylosing spondylitis Unbearable itch after withdrawal of antihistamines is not a common phenomenon. A PubMed search revealed no published reports of this association. However, there has been extensive discussion about the occurrence of pruritus after withdrawal of levocetirizine on several patient forums and blogs 5, 6. In some African countries, 70 percent of patients treated with chloroquine develop an itch. It can become serious enough that many are forced to discontinue the medication. Hello, My Wife has Malaria. She is Ghana XXXXXXX and needs to be seen by a specialist. In the mean time she has been given injections of chloroquine and anti malaria by a Pharmacist who works for her. I was wondering if anyone else was experiencing this and what they did to help it! I was reading online and some people had mentioned that the name brand Plaquenil didn't cause such a severe reaction. Itching after taking chloroquine Plaquenil and itching -, How a new understanding of itch leads to better pain. How does chloroquine prevent malariaPlaquenil make tongue starchy Itchy skin may indicate an allergy, along with hives or a rash causing your skin to become red, swollen and blistered, warns Other symptoms of an allergic reaction to multivitamins include swelling of the face, mouth, lips, tongue or throat. Get medical attention if you experience any of these side effects from taking a multivitamin. Supplements That Might Make You Itch. Itching and chloroquine - Doctor answers on HealthcareMagic. Does anyone else suffer from ITCHING? I have R A and.. But if the rash and itching started after you started the new medicine you should always check with your doctor because it could be an allergic reaction to one of the compounds that makes up the pill. Side effects of antimalarial drug can overlap with malaria symptoms. We evaluated 50 patients with vivax malaria in Mâncio Lima, Acre, treated with chloroquine and primaquine. Patients were evaluated for the presence of 21 symptoms before and after treatment and for reported side effects of these drugs after treatment was started. Note This document contains side effect information about hydroxychloroquine. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects.