She suffered from Sjogren syndrome and inflammatory arthritis and was currently treated with prednisone and methotrexate. She was previously treated with hydroxychloroquine (Plaquenil) 200mg bid (6.5mg/kg) for 10 years, which was stopped one year prior to presentation. Another medication that can be taken with plaquenil Hla-dr4 rheumatoid arthritis and hydroxychloroquine A 26-year-old black female presented in office for her annual comprehensive eye exam. Her medical history was significant for Plaquenil therapy spanning 12 years with a daily dose of 200mg twice daily. She presented with a best-corrected visual acuity of 20/20 OD and 20/20 OS. All preliminary testing revealed normal findings. Diagnosis Hydroxychloroquine-induced retinal toxicity Discussion. Chloroquine CQ and hydroxychloroquine Plaquenil HCQ have been used for many years, initially for the treatment of malaria but now more commonly for the treatment of inflammatory diseases such as rheumatoid arthritis and lupus 1. Plaquenil and Eye Problems. Plaquenil can cause serious vision problems that aren't always reversible. Tell your doctor immediately if you notice any changes in vision or if you've ever had vision. Review of systems: Blurred vision, halos, dry eye, dry mouth, gastroesophageal reflux, joint pain Pupils: Reactive to light in each eye from 5 mm in the dark to 2 mm in the light. Extraocular movements: Full, both eyes (OU) Confrontation visual fields: Full OU Intra-ocular pressure The optic nerves appeared healthy with a 0.3 cup-to-disc ratio. Past Ocular History: None Medical History: Sjogren syndrome and inflammatory arthritis, supraventricular tachycardia, anxiety, depression, peptic ulcer disease Medications: prednisone, methotrexate, amitriptyline, ranitidine, estradiol, tizanidine, diltiazem, Restasis Allergies: codeine, droperidol Family History: heart disease, arthritis, cancer Social History: occasional alcohol but no tobacco or intravenous drug use. Plaquenil eye test Plaquenil screening eye exam, hydroxychloroquine toxicity - A State of., Hydroxychloroquine Plaquenil Toxicity and Recommendations. Plaquenil malaria mechanismChloroquine hek293Hydroxychloroquine 200 mg tab generic plaquenilChloroquine syrup dosageChloroquine vs quinine Tell all of your health care providers that you take Plaquenil hydroxychloroquine. This includes your doctors, nurses, pharmacists, and dentists. A severe eye problem has happened with Plaquenil hydroxychloroquine. This may lead to lasting eyesight problems. The risk may be higher if you have some types of eye or kidney problems. Plaquenil Indications, Side Effects, Warnings -. Plaquenil Hydroxychloroquine - Side Effects, Dosage, Interactions - Drugs. My Take on New Ocular Screening Guidelines for Plaquenil RheumNow.. Recently, specialists have announced new guidelines for Plaquenil screenings because of associated retinal problems while taking Plaquenil. Also, the technology for detecting retinal changes has improved since the initial guidelines were set. The new guidelines recommend eye doctors perform a comprehensive eye exam, including the following Jan 05, 2020 Hydroxychloroquine Plaquenil and chloroquine cause ocular toxicity to various parts of the eye such as the cornea, ciliary body, and retina. Chloroquine can also induce cataract formation; however, no reports of hydroxychloroquine and cataract have been reported. This article focuses upon hydroxychloroquine retinopathy. Disease Eye damage due to Plaquenil is not common,” he says. “Rarely will anybody who has good vision and minimal symptoms develop loss of central vision or ability to read if annual screening is done and visual are symptoms reported as soon as they occur so the medication can be stopped if toxicity occurs.