The clinical trials on this list are for breast cancer treatment. NCI’s basic information about clinical trials explains the types and phases of trials and how they are carried out. Clinical trials look at new ways to prevent, detect, or treat disease. Chloroquine trade name Chloroquine phosphate tablets 500mg What do hydroxychloroquine do Rs is an emerging trend in cancer treatment. However, the value of autophagy inhibitors remains under debate. Thus, a meta-analysis was performed, aiming to evaluate the clinical value of autophagy-inhibitor-based therapy. Methods We searched for clinical studies that evaluated autophagy-inhibitor-based therapy in cancer. We extracted data from these studies to evaluate the relative risk RR. You may be offered the opportunity to take part in a clinical trial at some point during your treatment for breast cancer. Clinical trials are research studies that evaluate the safety and effectiveness of new treatment approaches for diseases. In some cases, a study may give you access to new. A Phase 2 Randomized, Double-blind Trial Evaluating the Effects of Chloroquine in Breast Cancer CUBiC The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Talk to your doctor for help in deciding if one is right for you. You may want to think about taking part in a clinical trial. Chloroquine breast cancer clinical trial Chloroquine & Hydroxychloroquine supporting chemo., Breast Cancer Clinical Trials & Research Memorial Sloan. Plaquenil and color visionPlaquenil taken with uroxatralChloroquine phosphate 500 mg side effects Nov 04, 2015 My oncologist is allowing me to be on this for a month and if I don't show continued improvement I need to stop. There is a clinical trial using this combination in IDH mutated cancers. Also, many GBM patients use these drugs too. Metformin impairs glycolysis energy production for the cancer cells and chloroquine inhibits autophagy dormancy. Chloroquine plaquil combinations - Ovarian cancer - Inspire. A Phase 2 Randomized, Double-blind Trial Evaluating the.. A trial of chemotherapy and. - Cancer Research UK. Chloroquine has demonstrated anti-tumor activities through autophagy inhibition and cell cycle disruption. This study aimed to assess the effect of single-agent chloroquine on breast tumor cellular proliferation in a randomized, phase II, double-blind, placebo-controlled, pre-surgical window of opportunity trial. Patients with newly diagnosed breast cancer were randomized 21 to chloroquine. Clinical trials are research studies that involve people. The clinical trials on this list are for breast cancer treatment. All trials on the list are supported by NCI. NCI’s basic information about clinical trials explains the types and phases of trials and how they are carried out. Clinical. These preclinical data highlight the relevance of a clinical trial combining chloroquine and TAM for the treatment of ER + in situ breast lesions Preventing Invasive Neoplasia with Chloroquine trial and suggest a clinical benefit of the addition of CQ to antiestrogen therapy for the treatment of ER + breast cancer. Furthermore, this study.