One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine (Plaquenil), a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. Is plaquenil safe for one kideny What time of day to take plaquenil Plaquenil depletes magnesium Hydroxychloroquine is a prescription drug. It comes as an oral tablet. Hydroxychloroquine is available as the brand-name drug Plaquenil. It’s also available in a generic version. Chloroquine and hydroxychloroquine belong to the quinolone family. They are related drugs with similar clinical indications for use and similar manifestations of retinal toxicity, although their therapeutic and toxic doses differ. Jan 05, 2020 Hydroxychloroquine is a well-tolerated medication for various rheumatologic and dermatologic conditions. Its main side effects are gastrointestinal upset, skin rash, headache, and ocular toxicity1. Within the eye, hydroxychloroquine can adversely impact the cornea, ciliary body, and retina1 It is imperative that patients and physicians are aware of and watch for this drug’s ocular side effects. Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress. Hydroxychloroquine cornea Protecting your eyesight when taking Plaquenil Lupus., Chloroquine and Hydroxychloroquine Toxicity Clinical Presentation Most common side effects of plaquenilLow-dose hydroxychloroquine in treatment of porphyriaTingling arms plaquenilPlaquenil pigmentation treatment Ocular toxicity from hydroxychloroquine may be seen in two distinct areas of the eye the cornea and the macula. The cornea may become affected relatively commonly by an innocuous vortex keratopathy and is characterized by whorl-like corneal epithelial deposits. PLAQUENIL hydroxychloroquine and the Eye Westford. Hydroxychloroquine toxicity - EyeWiki. Retinal toxicity associated with chronic exposure to.. At the initiation of treatment with hydroxychloroquine, the prescribing physician should refer the patient to an ophthalmologist. During the initial examination, it is recommended that the patient receive 1 a thorough ocular examination documenting any preexisting conditions, 2 a Humphrey visual field central 10-2 white-on-white pattern, and Hydroxychloroquine – what you can expect when starting treatment. This information sheet will help you understand what to expect when starting treatment with hydroxychloroquine. It is not a substitute for talking with your doctor, nurse or pharmacist. What is hydroxychloroquine? Hydroxychloroquine is a medicine used to Hydroxychloroquine has a lower risk of ocular toxicity, both corneal and retinal, compared with chloroquine. Smoking possibly reduces the efficacy of hydroxychloroquine, although studies have not usually confirmed this clinical impression. Hydroxychloroquine is considered safer than chloroquine during pregnancy and lactation.