Part of that is due to less exercise, part due to having no appetite thus feeling like anything I can get down is ok. Well, now I've been exercising at almost my pre-Lupus rate (ran a marathon a year before), eating a more moderate diet (clean protein, vegs & fruits), and am no longer taking that weight & bloat causing Prednisone (off Pred almost 2 yrs now). My question: Do you feel like you've gained weight on Plaquenil (ie without Prednisone)? Plaquenil and cataracts Medication for rheumatoid arthritis plaquenil I have been on plaquenil for many a year, and it has not affected my weight at all. If you go to or rxlist.com, neither of them list weight gain as a side effect, while they both list "nausea, vomiting, stomach pain; loss of appetite, weight loss" as side effects. Common hydroxychloroquine side effects may include headache, dizziness, ringing in your ears; nausea, vomiting, stomach pain; loss of appetite, weight loss; mood changes, feeling nervous or irritable; skin rash or itching; or. hair loss. I saw the GI doctor today I am SO TIRED of seeing doctors and after our brief meeting, he has me scheduled for a colonoscopy and upper GI scope/biopsy!I am very underweight and do have chronic diarrhea, but gosh, this seems invasive as a first step in trying to figure out anyone had chronic diarrhea/weight loss from Plaquenil? My Lupus has been really quiet for about 2 yrs, and I'm afraid to change anything. The Plaquenil drug side effects list weight loss, but some people have reported weight gain instead. My rheumy wants me to come down and then off my Plaquenil, but I've been resisting simply because I'm afraid to. Hydroxychloroquine and weightloss Abnormal Weight Gain and Gut Microbiota Modifications Are., Hydroxychloroquine Uses, Dosage & Side Effects - Is plaquenil same as hydroxychlorO hydroxychloroquinePlaquenil eye exam Hydroxychloroquine is a disease-modifying anti-rheumatic drug DMARDregulates the activity of the immune system, which may be overactive in some conditions. Hydroxychloroquine can modify the underlying disease process, rather than simply treating the symptoms. Hydroxychloroquine Side-effects, uses, time to work. Plaquenil, diarrhea and weight loss?. Hydroxychloroquine - Wikipedia. Eat 6 meals/day. Work on strength training to build your large muscle groups. Workout w heavier weights w fewer repetitions. Sleep at least 8 to 9 hrs/night. Hydrate well w water. Foods to help w healthy weight gain almonds, cashews, pecans, sunflower seeds, flax seeds, walnuts, hummus. Hydroxychloroquine sulfate and Weight loss - a real-world study. Summary Weight loss is found among people who take Hydroxychloroquine sulfate, especially for people who are female, 2-9 old, have been taking the drug for 1 - 2 years, also take medication Enbrel, and have Juvenile rheumatoid arthritis. Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more.