Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Chloroquine and proguanil dose Hydroxychloroquine 200 mg tab en espanol Toxic effect of chloroquine and advised to avoid direct exposure to sunlight. Keywords Chloroquine, Hyperpigmentation of skin, Connective tissue disorder Chloroquine has affinity for melanin and it gets con-centrated in pigmented melanin-containing structures which may explain its toxic effects on the eye kerato- Chloroquine diphosphate and hydroxychloroquine sul-fate, are administered for treatment of several dermato-logic and rheumatologic disorders, and they are known to cause hyperpigmentation of the oral mucosa 9,15. Systemic administration of these drugs for a prolonged period is responsible for the appearance of multifocal A differential diagnosis with hyperpigmentation caused by endocrine and metabolic disorders, the most closely-related disorders to drug-induced hyperpigmentation, and with hyperpigmentation of idiopathic origin, should be conducted. Drug-induced hyperpigmentation is a relatively frequent reason for consultation, especially in polypharmacy patients. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Chloroquine hyperpigmentation Drug-induced hyperpigmentation DermNet NZ, Hyperpigmentation of hard palate induced by chloroquine therapy Aralen online shoppingWhat stage of infection did the chloroquine treatWhy is the drug hydroxychloroquineChloroquine phosphate testing kitPlaquenil maculopathy report Skin Hyperpigmentation with Hydroxychloroquine Hydroxychloroquine Plaquenil is a common trade name is an anti-inflammatory oral medication that is commonly used to treat many autoimmune diseases. In the hair clinic, we use it for diseases such as lichen planopilaris, frontal fibrosing alopecia, pseudopelade and discoid lupus. Skin Pigmentation with Hydroxychloroquine Plaquenil.. Drug-Induced Hyperpigmentation Review and Case Series.. Hydroxychloroquine-induced Hyperpigmentation of the Skin.. Dec 15, 2017 Skin discolouration or hyperpigmentation is a sign of underlying health problems. Skin, the largest organ of the human body, is a mirror of your health. So whenever something goes wrong inside, it eventually starts reflecting on the skin. One such sign is hyperpigmentation, a sign from your skin that all is not well within your body. Some medications, such as plaquenil and minocycline, can cause permanent dark skin plaques, which resemble black and blue marks similar to morphea scleroderma. Cosmetically, pigmentation differences can be covered up with corrective cosmetics, such as Dermablend. Drug-Induced Hyperpigmentation caused by Minocycline Minocin Antibiotic Find patient medical information for Chloroquine Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.