The recurrent, painful tightening usually occurs in the calf muscles and can cause severe insomnia. The exact mechanism is unknown, but the cramps are probably caused by muscle fatigue and nerve dysfunction rather than electrolyte or other abnormalities. Hydroxychloroquine libido Can plaquenil cause loss of hearing Do you have to be weaned off of plaquenil Chloroquine sigma SIDE EFFECTS. The following adverse reactions have been identified during post-approval use of PLAQUENIL or other 4-aminoqunoline compounds. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. QUOTE=DawnI have been on plaquenil for around 8 months or so but these leg cramps have just gotten worse and the ladies I work with told me to get calcium with magnesium. That would help out with the leg cramps but I am worried with all the meds that I take I am afraid that it might interact with the meds. If you don't mind, could you tell me something? Do most people with RA continue to work full-time? I do, except that I called in sick today because I was up all night with leg cramps, but I'm finding it extremely difficult to stay awake for an eight hour day. I'm 52 and can't retire yet so I'm wondering what people do to make it through the day? Medications that are strongly associated with leg cramps include intravenous iron sucrose, conjugated estrogens, raloxifene, naproxen, and teriparatide. Nocturnal leg cramps are associated with vascular disease, lumbar canal stenosis, cirrhosis, hemodialysis, pregnancy, and other medical conditions. Does plaquenil cause leg cramps Hydroxychloroquine Oral Route Side Effects - Mayo Clinic, Foot and leg cramps Arthritis Information Side effects with plaquenilChloroquine phosphate structureHow does chloroquine phosphate workChloroquine help with payment for prescriptionsCan i get plaquenil in mexico Up to 60 percent of adults report that they have had nocturnal leg cramps. The recurrent, painful tightening usually occurs in the calf muscles and can cause severe insomnia. The exact mechanism. Nocturnal Leg Cramps - American Family Physician. Severe Leg Cramps" Rheumatoid Arthritis Community.. Stomach problems with Plaquenil • Johns Hopkins Arthritis.. Preventing Lupus Leg Cramps. Leg cramps can be caused by muscle strain or dehydration. If you are athletic, you should take precautions to ensure that you do not become dehydrated. Sometimes leg cramps are brought about because your extremities do not get an adequate blood supply when you are exercising. A low platelet count is a blood disorder that can sometimes be serious. This article looks at platelets and their role within the body. Find out about the many possible causes of a low count. Plaquenil “ Side Effects Dizzy, upset stomach, back pain and side pain, abdominal cramps, leg cramps, rapid heart rate, anxiety and body felt covered in bruises Before taking Plaquenil my only symptom.