It may have both an anti-spirochaete activity and an anti-inflammatory activity, similar to the treatment of rheumatoid arthritis. And caution is required if patients have certain heart conditions, diabetes, psoriasis etc. Extraerythrocytic malria and chloroquine Chloroquine phosphate chemical formula I had a skin rash from plaquenil hydroxychloroquine. I was put on a 21 day taper of prednisone. How long before the prednisone increases my odds of catching viruses? Pigmentary changes in skin and mucous membranes, bleaching of hair, and alopecia are usually reversible when therapy is discontinued.-AGEP should be distinguished from psoriasis, although this drug may precipitate attacks of psoriasis; it may be associated with fever and hyperleukocytosis. Common 1% to 10% Rash, pruritus Three anti-malarial drugs are prescribed for lupus symptoms. Hydroxychloroquine Plaquenil is the most commonly prescribed because it is generally believed to cause fewer side effects; chloroquine Aralen has a reputation for more serious side effects, but it may be prescribed in situations where hydroxychloroquine cannot be used. For prolonged treatment of lupus or arthritis, adverse effects include the acute symptoms, plus altered eye pigmentation, acne, anaemia, bleaching of hair, blisters in mouth and eyes, blood disorders, convulsions, vision difficulties, diminished reflexes, emotional changes, excessive coloring of the skin, hearing loss, hives, itching, liver problems or liver failure, loss of hair, muscle paralysis, weakness or atrophy, nightmares, psoriasis, reading difficulties, tinnitus, skin inflammation and scaling, skin rash, vertigo, weight loss, and occasionally urinary incontinence. The most common adverse effects are a mild nausea and occasional stomach cramps with mild diarrhea. For short-term treatment of acute malaria, adverse effects can include abdominal cramps, diarrhea, heart problems, reduced appetite, headache, nausea and vomiting. Plaquenil for skin rash Hydroxychloroquine Side-effects, uses, time to work, Plaquenil Side Effects Common, Severe, Long Plaquenil overdose fatal I can attest to being one of the most sensitive to drugs my docs have ever seen. When I first start a med, I have to split dose into 1/4's and add 1/4 more each week. Yes with plaquenil generic, I have itching, intense I could scratch through my skin. But it does calm down. I also get weird rashes but I get those from the Lupus. Plaquenil and itching -. Treating Lupus with Anti-Malarial Drugs Johns Hopkins.. Hydroxychloroquine Plaquenil. Skin rashes and pigment change. Atabrine, specifically, can cause yellow pigmentation of skin. Sometimes Plaquenil can also deposit in the tissues of the body and cause the skin to take on a greenish tone. Hi There, Ok, I just started taking Plaquenil 7 days ago and I just realized I am really really itchy. I looked down at my arms and I have red and white blotchy areas on my forarms. I am starting to itch in my scalp, back, stomach, face and arms now. I think this rash is just starting, so I don't know if it will Quinacrine Atabrine Quinacrine is another alternative, but it is prescribed less often because it can sometimes cause a yellow discoloration of the skin. It is sometimes given in addition to hydroxychloroquine if the Plaquenil on its own is not adequately managing symptoms. Only a compounding pharmacist can dispense Quinacrine as tablets are.