Hydroxychloroquine is available as the brand-name drug Plaquenil. Generic drugs usually cost less than the brand-name version. Hydroxychloroquine may be used as part of a combination therapy. Chloroquin functional groups Methotrexate plaquenil Many medications have been designed to treat migraines. Medications used to combat migraines fall into two broad categories Pain-relieving medications. Also known as acute or abortive treatment, these types of drugs are taken during migraine attacks and are designed to stop symptoms. Preventive medications. These may occur for the first few days a person takes the drug while the body adjusts to the medication. Loss of appetite, tiredness, weakness, or headache are uncommon side effects and typically go away over time. Rare complications. The greatest concern people have when taking hydroxychloroquine is related to vision. Plaquenil is the brand name of hydroxychloroquine, a drug used to prevent or treat malaria 2. Plaquenil is also used for long-term treatment of autoimmune diseases such as rheumatoid arthritis RA and systemic lupus erythmatosis. According to the Mayo Clinic, it can take up to six months' constant use before an effect is seen in RA 1. Hydroxychloroquine is used to treat lupus erythematosus and rheumatoid arthritis. It isn’t fully understood how this drug works to treat lupus erythematosus or rheumatoid arthritis. That means you may need to take it with other drugs. It treats malaria by killing the parasites that cause the disease. Hydroxychloroquine cure headaches Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus., Drug spotlight on hydroxychloroquine Lupus Foundation of America Can plaquenil cause visual fieldHydroxychloroquine sulfate rashChloroquine for typhoidChloroquine nightmaresPlaquenil alcohol interaction Plaquenil and Headache - from FDA reports Summary Headache is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months, also take medication Enbrel, and have Pain. This study is created by eHealthMe based on reports of 57,706 people who have side effects when taking. Will you have Headache with Plaquenil - eHealthMe. Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis.. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. Hydroxychloroquine is a quinoline medicine used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Effects of hydroxychloroquine? Hydroxychloroquine is a relatively well tolerated medicine. The most common adverse reactions. reported are stomach pain, nausea, vomiting, and headache. These side effects can often be lessened by taking hydroxychloroquine with food. Hydroxychloroquine may also cause itching in some people. Hydroxychloroquine is usually taken with food or milk to prevent stomach upset. The dosage and length of treatment are based on your medical condition and response to therapy. In children, dosage.