I was diagnosed with discoid lupus 18 years ago and was prescribed Plaquenil, which I have taken since then. In October 2012, I was also diagnosed with Sjogrens Syndrome but, as I was already taking Plaquenil, was advised the treatment was the same for Sjogrens. How does plaquenil work for arthritis Hydroxychloroquine side effects rash The main inclusion criteria were age 18 years, serum hemoglobin level ≥10 g/dL, white blood cell count ≥4000/mL, plasma platelet count in the range of 150.000–400.000/mL, glomerular filtration rate ≥70 cc/mL, serum Aspartat aminoteransferase AST and Alanin Aminoteransferase ALT levels less than 1.5-times of the upper normal limit. SIDE EFFECTS. The following adverse reactions have been identified during post-approval use of PLAQUENIL or other 4-aminoqunoline compounds. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. Nov 16, 2018 A low platelet count is a blood disorder that can sometimes be serious. This article looks at platelets and their role within the body. Find out about the many possible causes of a low count. From research I have done online, I gather that low white cell count can also be a symptom of the Sjogrens in itself. At a recent medical with my doctor, blood tests were taken and I had a call a couple of days later telling me to stop taking g Plaquenil immediately as I have a very low white cell count and that it is sometimes a side effect of Plaquenil. Plaquenil and low white blood count What does a Low White Blood Cell Count Indicate?, Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses Plaquenil peripheral neuropathySandoz hydroxychloroquineChloroquine and malaria treatmentCan hydroxychloroquine be used for mrsa Anemia or low white blood count Although Sjögren’s syndrome is often treatable, this disease is poorly understood and cannot be cured with current medications. Sjögren’s syndrome is often not diagnosed correctly. In part, this is because dry eyes and dry mouth are common symptoms. Symptoms of Sjögren's Syndrome Johns Hopkins Sjögren’s.. Low platelet count thrombocytopenia Causes, treatment, and.. Link between low white cell count and taking Plaquenil?. Blood Disorders. According to the New Zealand Dermatological Society, Plaquenil can cause abnormalities in blood counts. An abnormally low number of white blood cells can lead to infection, because white blood cells defend the body against bacteria. Low platelet count thrombocytopenia can lead to easy bleeding and bruising. My Absolute Neutrophils good indicator of immune system function didn't get suppressed to a NORMAL range until I increased the Plaquenil to 600mg/day while still taking the Prednisone. In addition, my white blood cell count was still within a normal range. Expand. Side effects include irritability, headache, weakness, hair lightening or loss, stomach upset, nausea, dizziness, muscle pain, rash and itching. Rarely, hydroxychloroquine can affect the bone marrow leading to reduced white blood cells leukopenia or platelets thrombocytopenia and abnormal red blood cells.