Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Chloroquine diphosphate Chloroquine for fish Chloroquine malaria Hydroxychloroquine uses in dermatology The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is. For the Consumer. Continuing ringing or buzzing or other unexplained noise in the ears. feeling of constant movement of self or surroundings. irritability. nausea. nervousness. nightmares. sensation of spinning. shakiness and unsteady walk. uncontrolled eye movements. unsteadiness, trembling, or. Plaquenil side effects Get emergency medical help if you have signs of an allergic reaction to Plaquenil hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Taking Plaquenil long-term or at high doses may cause irreversible damage to the retina of your eye. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Complete list of side effects of plaquenil PLAQUENIL Side Effects & Interactions RxSaver by RetailMeNot, Plaquenil Side Effects Common, Severe, Long Term - Drug aralen Symptoms of a serious allergic reaction may include rash, itching/swelling especially of the face/tongue/throat, dizziness, trouble is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or the US -Call your doctor for medical advice about side effects. HYDROXYCHLOROQUINE - ORAL Plaquenil side effects, medical.. Plaquenil Uses, Dosage & Side Effects -. Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus.. Serious side effects have been reported with Plaquenil including the following Heart failure. Plaquenil can cause weakening of the heart muscle, resulting in heart your healthcare provider right away if you have some or all of the following symptoms of heart failure. Based on this information, possible bothersome but usually not dangerous side effects of Plaquenil may include Nausea and vomiting. Diarrhea and abdominal pain. Headaches. Dizziness or a spinning sensation vertigo. Ringing in the ears tinnitus. Loss of appetite. Nightmares. Hydroxychloroquine is the generic form of Plaquenil but the side effects are the same. My thigh muscles are so sore I can hardly walk, sit or stand. Stairs are a TRUE challenge. I have to struggle up and down taking only one step at a time using only one leg at a time.