I've been on plaquenil for 6 months for suspected Sjogren's syndrome (I don't have antibodies for Sjorgren's or Lupus but I do have Hashimoto's and have all the symptoms for Sjorgren's so the rheumatologist suggested a trial of plaquenil). Basically I've been on the drug since January and saw the rheumatologist on Wednesday to see how things are going. Plaquenil toxicity lips Taking plaquenil can i drink alcohol When my doc was telling me about. the plaquenil and some symptoms I might experience, he told me to stop taking it if I felt weird in any way. ok, my tongue swelled and felt itchy and burny. Well, after day three I decided it wasn't a minor thing and called my doc. So now, no more plaquenil. I am on nothing and I'm in pain all over again. yay me. As the drug becomes less effective, a patient in remission will discover that his or her joint symptoms have returned. Switching RA Medications May Help Fortunately, an antibody that dampens the benefits of one biologic drug typically doesn’t target others, notes Dr. Hardin. With the symptoms you have, I would have thought your consultant could make a diagnosis based on those alone. As for plaquenil, I know it helps my fatigue a lot I have recently had to halve my dose due to concerns about macular degeneration and its affected my energy levels hugely. I do think it's helped with fatigue and muscle pain but it's hard for me to compare to Xmas as when the improvement is so gradual I think it's really hard to notice on a gradual basis. I *think* I'm improving but it's been a gradual process and I said to him that it's quite hard to tell how much of an improvement I'm feeling. Stopped plaquenil now symptoms have returned Plaquenil Withdrawal – Life As An Anomaly, Why Your RA Went Into Remission, but Relapsed Arthritis. Plaquenil cross eyes Certified integrative health coach Luanna Barker of New York says that RA and lupus patients who have to stop taking Plaquenil can focus on alternative methods of treatment in the interim, until. Plaquenil Shortage Leaves RA, Lupus Patients in Pain and.. Hydroxychloroquine plaquenil withdrawl? - LUPUS UK. What is the correct way to discontinue use of plaquenil?. If you experience any of the following symptoms, call your doctor immediately reading or seeing difficulties words, letters, or parts of objects missing. sensitivity to light. blurred distance vision. seeing light flashes or streaks. difficulty hearing. ringing in ears. muscle weakness. Return of symptoms. This would be quite variable and it may take days, weeks or months before any relapse occurs. A lot depends on the type and intensity of your original disorder. Did your ANA level fall when you were started on plaquenil? Relapse would most likely consist of return of your original symptoms. Plaquenil works well, but very slowly. You will need to give it at least a 6 months trial, and don't expect much in the way of results for a couple of months. After that, you'll probably look back and realize one day that you just don't feel as sore as you did three or four months back.